ROBUST SYSTEM PUMPS TO SEPARATE BIOMOLECULES FROM AQUEOUS AND ORGANIC SAMPLES
The system pump capabilities can be extended
• Pumps are constructed of PEEK polymer, the same material used in chromatography tubing
• Incorporate buffer inlets for multiple buffer selection
• Add a buffer-blending module for automated method scouting
SAMPLE LOADING SOLUTIONS SPANNING LARGE VOLUME RANGES AND THROUGHPUT REQUIREMENTS
• Use standard fixed-size sample loops and dynamic loops
• Perform automated, accurate, and reproducible multiple injections (5 µl–5 ml) using an autosampler
• Use a sample loading pump (flow rates of up to 100 ml/min) and an air sensor for:
– Loading of large sample volumes directly to the column
– Extending the life span of system pumps
VARIOUS COLUMN CONFIGURATIONS FOR COLUMN SCOUTING AND REDUCED NEED TO RE-PLUMB
• Add a single column switching module to connect up to five columns
• Add multiple column switching valves
– For multi-dimensional purification
– For reverse flow capability, which is ideal for column cleaning
UV MODULES THAT COME STANDARD WITH CONDUCTIVITY MONITORS PROVIDE OPTIMAL RESULTS
• The single-wavelength detector module utilizes an innovative LED light source that offers extended lamp life
• The multi-wavelength detector module can monitor up to four wavelengths simultaneously between 190–800 nm
MULTIPLE SAMPLE COLLECTION OPTIONS TO COLLECT EVERY DROP OF YOUR PRECIOUS PURIFIED SAMPLE
• Use the BioFrac™ fraction collector — choose from rack options such as 96-well microtiter plates, standard 12 mm tubes, 15
and 50 ml conical tubes
• Add one or more 12-port outlet modules to collect your sample into any other types of vessel
DUAL-GRADIENT PUMP SYSTEM
ACCURATE GRADIENTS FOR HIGH-RESOLUTION SEPARATIONS FOR ANY APPLICATION
Includes two gradient pumps and a mixer module to create precise gradients from two buffers.
- Available in 0.001–10 ml/min or 0.01–100 ml/min formats
- Up to 3,650 psi and 1,450 psi for the 10 ml/min and 100 ml/min pumps, respectively
- Used with a wide range of media, from soft, large bead media to small, rigid media
DUAL-GRADIENT PUMP SYSTEM WITH BLENDING QUARTENARY VALVE
AUTOMATED GRADIENTS AND BLENDING FOR RAPID SCOUTING AND METHOD DEVELOPMENT
Includes two gradient pumps, a mixer module, and a quaternary valve for buffer-blending and scouting applications.
- Available in 0.001–10 ml/min (max. 3,650 psi) and 0.01–100 ml/min (max. 1,450 psi) formats
- Automated gradient and buffer-blending capabilities
- Gradient separations at different pH values for rapid method development
- Flow rates of up to 20 ml/min and 200 ml/min for the 10 ml/min and 100 ml/min pumps, respectively
DUAL-GRADIENT PUMP SYSTEM WITH BLENDING QUARTENARY VALVE AND TWO 8-PORT BUFFER INLETS
AUTOMATED BUFFER BLENDING COMBINED WITH AUTOMATED GRADIENTS USING A WIDE VARIETY OF BUFFERS FOR RAPID EXPANDED SCOUTING
Includes two gradient pumps, a mixer module, two inlet valves for automated buffer selection, and a quaternary valve for buffer-blending and scouting applications.
- Available in 0.001–10 ml/min (max. 3,650 psi) and 0.01–100 ml/min (max. 1,450 psi) formats
- Automated buffer gradient and buffer-blending capabilities
- Buffer screening and gradient separations at different pH values
- Additional inlets for buffer, cleaning, and storage solutions for fully automated workflows and walk-away convenience
- Flow rates of up to 20 ml/min and 200 ml/min for the 10 ml/min and 100 ml/min pumps, respectively
DUAL-GRADIENT PUMP SYSTEM WITH TWO 8-PORT BUFFER INLETS
AUTOMATED BUFFER SELECTION AND SCOUTING
Includes two gradient pumps, a mixer module, and two inlet valves.
- Available in 0.001–10 ml/min (max. 3,650 psi) and 0.01–100 ml/min (max. 1,450 psi) formats
- Additional inlets for buffer and cleaning, and storage solutions for fully automated workflows and walk-away convenience
DUAL-GRADIENT PUMP SYSTEM WITH AN 8-PORT BUFFER INLET
AUTOMATED BUFFER SELECTION AND SCOUTING
Includes two gradient pumps, a mixer module, and a single inlet valve
- Available in 0.001–10 ml/min (max. 3,650 psi) and 0.01–100 ml/min (max. 1,450 psi) formats
- Additional inlets for buffer and cleaning, and storage solutions for fully automated workflows and walk-away convenience
MANUAL SAMPLE LOADING
SMALL SAMPLE VOLUME INJECTIONS USING FIXED OR DYNAMIC LOOPS
Includes an 8-port inject valve and a fixed sample loop.
- Highly reproducible sample injections
- Sample injection integrated into method
- Multiple injections of different volumes using a dynamic loop
AUTOMATED SAMPLE LOADING
LARGE SAMPLE VOLUME INJECTIONS AND AUTOMATED REPEAT LOADING OF SAMPLES
Includes a sample pump with a pressure sensor.
- Dedicated pump for loading sample, eliminating contamination of system pump
- Automated loading of large volume samples either directly or via sample loops
- Flow rate of up to 100 ml/min at 1,450 psi
AUTOSAMPLER
AUTOMATED INJECTION OF A WIDE VARIETY OF SAMPLES
Includes a C-96 autosampler and a sample carousel.
- Various carousel types available based on the number and volume of samples
- Automated loading of up to 96 samples in a sequence of experiments
- Automated sample dilutions prior to loading
AUTOMATED SAMPLE LOADING WITH ONE 8-PORT SAMPLE INLET
LARGE SAMPLE VOLUME INJECTIONS AND AUTOMATED REPEAT LOADING OF SAMPLES
Includes an 8-port inject valve, a sample pump, a sample inlet valve, and a fixed loop.
- Dedicated pump for loading sample, eliminating contamination of system pump
- Sequential automated purification of up to 8 large volume samples
- Automated sample selection of up to 8 samples by inlet valve
- Flow rate of up to 100 ml/min at 1,450 psi
- Coming soon
AUTOMATED SAMPLE LOADING WITH TWO 8-PORT SAMPLE INLETS
LARGE SAMPLE VOLUME INJECTIONS AND AUTOMATED REPEAT LOADING OF SAMPLES
Includes an 8-port inject valve, a sample pump, two sample inlet valves, and a fixed loop.
- Dedicated pump for loading sample, eliminating contamination of system pump
- Sequential automated purification of up to 15 large volume samples
- Flow rate of up to 100 ml/min at 1,450 psi
- Automated sample selection of up to 15 samples by two sample inlet valves
- Coming soon
SINGLE COLUMN
CONNECTION TO ANY COLUMN AND MEDIA TYPE
For use with most commercially available self-packed, prepacked, glass, or stainless steel lab-scale columns or cartridges.
5-COLUMN SCOUTING / SCREENING
CONNECTION OF UP TO FIVE COLUMNS
Includes a 12-port column switching valve with reverse flow capability for increased flexibility in column and media selection.
- Rapid screening of up to 5 columns and media in automated sequence
- Reverse flow capability for concentrated fractions and column cleaning
- Built-in pressure sensors protect columns from overpressurizing and compacting
- Differential pressure sensing capability for monitoring column health
2 x 5-COLUMN SCOUTING / SCREENING
CONNECTING UP TO TEN COLUMNS AND PERFORMING TANDEM PURIFICATIONS
Includes two 12-port column switching valves with reverse flow capability for increased flexibility in column and media selection.
- Rapid screening of up to 10 columns and media in automated sequence
- Reverse flow capability for concentrated fractions and column cleaning
- Built-in pressure sensors protect columns from overpressurizing and compacting
- Differential pressure sensing capability for monitoring column health
- Coming soon
3 x 5-COLUMN SCOUTING / SCREENING
CONNECTING UP TO 15 COLUMNS AND PERFORMING TANDEM PURIFICATIONS
Includes three 12-port column switching valves with reverse flow capability for increased flexibility in column and media selection.
- Rapid screening of up to 15 columns and media in automated sequence
- Reverse flow capability for concentrated fractions and column cleaning
- Built-in pressure sensors protect columns from overpressurizing and compacting
- Differential pressure sensing capability for monitoring column health
- Coming soon
SINGLE-WAVELENGTH DETECTOR
LED-BASED SINGLE LIGHT SOURCE DETECTION WITH CONDUCTIVITY MONITORING
Includes a high-accuracy single-wavelength detector with integrated conductivity.
- Long-life LED-based light source (255 and 280 nm)
- Integrated conductivity detector (0.01–999 mS/cm)
MULTI-WAVELENGTH DETECTOR
SIMULTANEOUS FOUR-WAVELENGTH DETECTION WITH CONDUCTIVITY MEASUREMENT
Includes a four-wavelength detector with integrated conductivity.
- 4 user-defined wavelengths (190–800 nm)
- Integrated conductivity detector (0.01–999 mS/cm)
- Detection of peptides, proteins, nucleic acids, and specific chromophores such as hemoglobin
SINGLE-WAVELENGTH DETECTOR WITH pH MONITORING
LED-BASED SINGLE LIGHT SOURCE DETECTION WITH CONDUCTIVITY AND pH MONITORING
Includes a high-accuracy single-wavelength detector with integrated conductivity and pH detector, and a valve.
- Long-life LED-based light source (255 and 280 nm)
- Integrated conductivity detector (0.01–999 mS/cm)
- Full-range pH detection, includes pH probe and valve-based flow cell for convenient bypass, calibration, and storage
MULTI-WAVELENGTH DETECTOR WITH pH MONITORING
SIMULTANEOUS FOUR-WAVELENGTH DETECTION WITH CONDUCTIVITY AND pH MONITORING
Includes a four-wavelength detector with integrated conductivity and pH detector, and a valve.
- 4 user-defined wavelengths (190–800 nm)
- Detection of peptides, proteins, nucleic acids, and specific chromophores such as hemoglobin
- Integrated conductivity detector (0.01–999 mS/cm)
- Full-range pH detection, includes pH probe and valve-based flow cell for convenient bypass, calibration, and storage
BIOFRAC FRACTION COLLECTOR
IDEAL FOR ANALYTICAL AND PREPARATIVE CHROMATOGRAPHY APPLICATIONS
Includes a BioFrac fraction collector.
- Basic or complex fraction collection schemes for flow rates of up to 100 ml/min.
- Flexibility with numerous collection rack options such as microtiter plates, centrifuge tubes, 15 and 50 ml conical tubes, and bottles
- Integrated valve for diverting flow to waste
BIOFRAC FRACTION COLLECTOR WITH ONE 12-PORT OUTLET
IDEAL FOR ANALYTICAL AND PREPARATIVE CHROMATOGRAPHY APPLICATIONS
Includes a BioFrac fraction collector and a 12-port outlet valve.
- Basic or complex fraction collection for flow rates of up to 100 ml/min.
- Flexibility with numerous collection rack options
- Integrated valve for diverting flow to waste
- Outlet valve for additional large volume collection options
- Coming soon
BIOFRAC FRACTION COLLECTOR WITH TWO 12-PORT OUTLETS
IDEAL FOR ANALYTICAL AND PREPARATIVE CHROMATOGRAPHY APPLICATIONS
Includes a BioFrac fraction collector and two 12-port outlet valves.
- Basic or complex fraction collection schemes for flow rates of up to 100 ml/min.
- Flexibility with numerous collection rack options
- Integrated valve for diverting flow to waste
- Two outlet valves for maximum large volume collection options
- Coming soon
LARGE VOLUME COLLECTION — ONE 12-PORT OUTLET
IDEAL FOR PREPARATIVE CHROMATOGRAPHY APPLICATIONS
Includes a single 12-port outlet valve.
- Outlet valve for additional large volume collection options
- Coming soon
LARGE VOLUME COLLECTION — TWO 12-PORT OUTLETS
IDEAL FOR PREPARATIVE CHROMATOGRAPHY APPLICATIONS
Includes two 12-port outlet valves.
- Two outlet valves for maximum large volume collection options
- Coming soon
