Introducing Nuvia™ S Media


Nuvia S is an ultra high-capacity strong cation exchanger designed for optimal bioprocessing performance. It is built on the macroporous rigid UNOsphere™ base matrix with proprietary surface extender technology. The innovative design of Nuvia S gives the media superior binding capacity across a range of both pH and conductivity and over a broad range of flow rates.

Binding of polyclonal huIgG by Nuvia S media at various linear velocities

Graph A Graph B
A, binding capacity of a (1.1 x 20 cm) Nuvia S media column. B, comparison of a (1.9 x 9.5 cm) Nuvia S media column binding capacity with commercially available CEX media. (green), Nuvia S; (pink), CEX 1; (yellow), CEX 2; (blue), CEX 3.

The unique performance characteristics of Nuvia S make it suitable for both capturing and polishing steps of protein therapeutics. Nuvia S delivers value and flexibility by allowing users to achieve higher binding capacity at faster flow rates. Less media is needed and smaller columns can be used to purify a given amount of protein. Additionally, Nuvia S is an exceptional tool for removing product-related contaminants such as mAb fragments and aggregates.

Get a taste of high-capacity performance.

It's time to add Nuvia S to your solutions menu, to deliver robust, reproducible, efficient purifications time after time.


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