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Biomarker Discovery Using SELDI Technology


Proper study and experimental design coupled with the correct data analysis approach are critical components of successful biomarker discovery, no matter which technology, platform, or workflow is used. Bio-Rad has produced two in-depth guides to provide researchers with strategies for success.

The first guide, Biomarker Discovery Using SELDI Technology — A Guide to Successful Study and Experimental Design, provides a series of general guidelines for effective study design using virtually any proteomics technology, and gives specific recommendations for using the ProteinChip® surface-enhanced laser desorption/ionization (SELDI) system.


This guide also includes:

  • Guidelines for proper sample selection, collection, handling, and storage
  • Instructions for planning the experimental workflow
  • Tips on improving reproducibility through standard operating procedures
  • Important considerations for data analysis implementation
  • Optimized methods and protocols for serum or plasma analysis



Take a look. Click below to view a few sample pages.


The second guide, Biomarker Discovery Using SELDI Technology — A Guide to Data Processing and Analysis Using ProteinChip® Data Manager Software, is a comprehensive resource for data analysis workflows, guidelines, and specific recommendations for analyzing biomarker discovery data.


The guide covers:

  • General data analysis workflows
  • Data organization
  • Data processing steps, including baseline subtraction, normalization, and spectrum alignment
  • Statistical analysis using P values and ROC curves, hierarchical clustering, and principal component analysis
  • Glossary of software terms



Take a look. Click below to view a few sample pages.


To request your free printed copy or PDF of Biomarker Discovery Using SELDI Technology — A Guide to Successful Study and Experimental Design or Biomarker Discovery Using SELDI Technology — A Guide to Data Processing and Analysis Using ProteinChip® Data Manager Software, please answer a few short questions and provide your contact information below.

  1. What technology or technologies are you currently using for protein biomarker discovery? Check all that apply.*

    SELDI

    MALDI-MS

    LC/MS

    Protein microarrays

    None. I don't currently perform biomarker discovery.

    Other

  2. If other, please specify.

  3. Which of the following best describes your role:*

    Chief Scientist/Principal Investigator/Research Director/VP of Research

    Laboratory Supervisor/Manager

    Laboratory Technician

    Postdoctoral Researcher/Graduate Student

    Purchasing Manager/Agent

    Other

  4. If other, please specify.

  5. I would like to receive the following copies of the Biomarker Discovery Using SELDI Technology Guides. Check all that apply.*

    Printed copy — A Guide to Successful Study and Experimental Design

    PDF — A Guide to Successful Study and Experimental Design

    Printed copy — A Guide to Data Processing and Analysis Using ProteinChip® Data Manager Software

    PDF — A Guide to Data Processing and Analysis Using ProteinChip® Data Manager Software


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